Correlation between Apolipoprotein B-to-Apolipoprotein A1 Ratio and Total-to-HDL-Cholesterol Ratio in a Healthy Population: Should Castelli Index be Updated?

نویسندگان

  • DANIEL A. SINIAWSKI
  • WALTER MASSON
  • PATRICIA SORROCHE
  • LILIANA CASAÑAS
  • JUAN KRAUSS
  • ARTURO CAGIDE
  • Daniel A. Siniawski
چکیده

Background The total cholesterol/HDL cholesterol ratio (TC/HDL-Cr) was proposed as a marker of coronary risk about 25 years ago by Dr. William Castelli and the suggested target was <4.5. The INTERHEART study showed that the ApoB / ApoA ratio is a predictor of cardiovascular events higher than the TC / HDLr. Many laboratories in our country do not have the technology to accurately measure apolipoproteins.

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تاریخ انتشار 2011